The clearest answer in HIV confirmation testing: INNO-LIA® HIV I/II Score

When you are confronted with repeatedly reactive HIV screening patient test results it is strongly recommended1,2,3,4 that you confirm these results with other reliable techniques, such as the INNO-LIA™ HIV I/II Score immunoblot assay.

The INNO-LIA HIV I/II Score test contains recombinant proteins and synthetic peptides from HIV-1 and HIV-2 as well as a synthetic peptide from HIV-1 group O. These carefully selected antigens are coated at optimal concentrations as discrete lines on a nylon strip with plastic backing.

This immunoblot test detects seroconversion earlier than other confirmation technologies and gives less indeterminate results5-6. This reduces the need for repeated testing and thus limiting extra costs.

Compared to other testing technologies the INNO-LIA HIV I/II Score assay provides clear differentiation of HIV-1 and HIV-2 infections6-7-8 - which allows for much more adequate patient treatment.

 

So, here are some of the key advantages of using our gold standard immunoblot assay for HIV confirmation testing:

  • It’s the latest generation of a reference test with more than 25 years of accumulated and widely documented HIV testing results across the world.
  • It reliably confirms and differentiates HIV-1, HIV-1 group O, and HIV-2.
  • It gives a low number of indeterminate results.
  • It comes with ready-to-use and color coded reagents.
  • It offers clear cut, standardized and objective reading and interpretation of results.
  • It features flexible strip processing with both short and overnight procedures plus efficient walk-away automation; read the results when you are ready.

Download our leaflet below for full background information about the characteristics and references of the INNO-LIA Score product range, or click here to go to the INNO-LIA HIV I/II Score product page.

The South West Area Mesothelin and Premetrexed trial (SWAMP)

 

References:

  1. CDC Updated Recommendations for Laboratory Testing for the Diagnosis of HIV infection (published June 27, 2014)
  2. Public Health England – UK Standards for Microbiology Investigations / HIV screening and confirmation (Issue date 03.01.17)
  3. WHO guidelines – Screening donated blood for Transfusion-Transmissible Infections & Consolidated guidelines on HIV testing Services (July 2015)
  4. European guidelines: Guide to the preparation, use and quality assurance of blood components.  Recommendation No.R(95) 15
  5. Comparison studies performed at Fujirebio Europe N.V. using BBI seroconversion and low-titer panels.
  6. WHO report 16 “HIV ASSAYS: OPERATIONAL CHARACTERISTICS” – 2009
  7. Test performance data – IFU INNO-LIA™ HIV I/II Score assay
  8. Hønge BL et al. HIV Medicine (2018). The challenge of discriminating between HIV-1, HIV-2 and HIV-1/2 dual infections.